The GOAT ANTI HUMAN DEFENSIN BETA 2 Antibody from MyBioSource.com is a Goat Polyclonal antibody to DEFB4A, DEFB4B, Defensin, beta 2, and HBD-2. This antibody recognizes Human antigen. The GOAT ANTI HUMAN DEFENSIN BETA 2 Antibody has been validated for the following applications: ELISA, Functional Assay, Immunohistochemistry, and Western Blot.
Description
Goat anti Human Defensin beta 2 polyclonal antibody recognizes human Defensin beta-2 (BD-2), a ~4.3kDa cationic antimicrobial peptide, also known as Beta-defensin 4A or Skin-antimicrobial peptide 1 (SAP-1) expressed primarily by epithelial cells of the respiratory tract and skin, and an important component of the innate immune response against microbial infections. Expression of BD-2 is induced during inflammation in response to bacterial products and cytokines, and is initially expressed in a precursor form, which is cleaved to release the C-Terminal active portion of the protein which is secreted by the neutrophil and binds to bacterial membranes causing their disruption